Approximately 200 meters north of the theater, starting from the southern corner of the Bath of Nero and extending westward from the northern face of the Late Antiquity wall to the inner harbor, the Harbor Street is the main spine of the city. This street passes through the middle of the public center of the city along a north-south axis extending from the Harbor Agora to the Central Agora. Thus, it shapes the city center, which is concentrated to the east of the bay, and forms the focus of a network that spreads throughout the city with side streets.

The Harbor Street was largely submerged along with the inner harbor on the eastern side of Patara Bay, probably as a result of a tectonic collapse. Surrounded by porticos and shops on the east and west sides, the street reaches the North Gate of the West Stoa of the Central Agora at its southern end. While it is expected that there are alleys to the east and west as you go in the direction of the harbor, there are spaces with shops behind the west portico along the street.

With a width of 12.6 meters, Harbor Street ranks second in terms of length among the streets measured in Lycia to date, but only a 100-meter section of it could be uncovered due to high ground water. This north-south aligned street must have intersected with another east-west aligned street in front of the Corinthian Temple, although it has not yet been identified.

Between the streets and alleys that intersect each other perpendicularly, there are buildings with facades facing the streets and where façade architecture is at the forefront. The rows of shops behind the West Porticus increased the commercial and social mobility of the Harbor Street.

Three main architectural phases have been identified on Harbor Street:

•  The first phase belongs to the Trajan period, during which the western portico and the street were reorganized.

•  The second phase includes the reconstruction and repairs after the earthquake of 141/142 AD.

•  The third phase probably refers to the reconstruction after the earthquake of 240 AD.

Archaeological studies on the western portico show that the last architectural phase was used until the 6th century AD without major changes, with minor repairs and structural transformations.